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Subepithelial mucinous corneal dystrophy

AI overview

Subepithelial mucinous corneal dystrophy (SMCD) is a rare form of corneal dystrophy affecting the eye.

Key points
  • SMCD is a rare form of corneal dystrophy.
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    is a rare form of corneal dystrophy
  • It was first described in 1993 by Feder et al.
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    It was first described in 1993 by Feder et al.
  • Deposits of glycosaminoglycan were found anterior to Bowman layer.
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    Anterior to Bowman layer, deposits of glycosaminoglycan were detected
  • The glycosaminoglycan deposits were identified as chondroitin-4-sulfate and dermatan sulfate.
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    identified as chondroitin-4-sulfate and dermatan sulfate
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Subepithelial mucinous corneal dystrophy
A diffuse haziness is present in the papillary region of the cornea in association with discrete opacities. (Reproduced in Klintworth et al. with permission from Feder et al.)
SpecialtyOphthalmology

Subepithelial mucinous corneal dystrophy (SMCD), a condition of the eye, is a rare form of corneal dystrophy. It was first described in 1993 by Feder et al.[1] Anterior to Bowman layer, deposits of glycosaminoglycan were detected and identified as chondroitin-4-sulfate and dermatan sulfate.[citation needed]

  1. Feder RS, Jay M, Yue BY, Stock EL, O'Grady RB, Roth SI (August 1993). "Subepithelial mucinous corneal dystrophy. Clinical and pathological correlations". Arch. Ophthalmol. 111 (8): 1106–14. doi:10.1001/archopht.1993.01090080102025. PMID 8352693.{{cite journal}}: CS1 maint: deprecated archival service (link)