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Multifocal choroiditis and panuveitis

AI overview

Multifocal choroiditis and panuveitis (MCP) is an inflammatory disorder of unknown etiology, affecting the choroid, retina, and vitreous of the eye that presents asymmetrically, most often in young myopic women with photopsias, enlargement of the physiologic blind spot and decreased vision.

Key points
  • It is an inflammatory disorder of unknown etiology
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    an inflammatory disorder of unknown etiology
  • It presents asymmetrically
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    presents asymmetrically
  • It most often occurs in young myopic women
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    most often in young myopic women
  • The first description of the disease was written in 1973
    source quote
    The first description of the disease was written in 1973.
Symptoms
  • Blurry vision, with or without sensitivity to light
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    blurry vision, with or without sensitivity to light
  • Blind spots
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    blind spots
  • Floaters
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    floaters
  • Eye discomfort
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    eye discomfort
  • Perceived flashes of light
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    perceived flashes of light
  • Photopsias
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    photopsias
  • Enlargement of the physiologic blind spot
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    enlargement of the physiologic blind spot
  • Decreased vision
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    decreased vision
Diagnosis
  • Fluorescein angiography uses a special dye and camera to study blood flow in the back layers of the eye
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    A test called flourescein angiography uses a special dye and camera to study blood flow in the back layers of the eye.
  • Lesions in the eye appear as fluorescent spots
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    lesions in the eye will appear as fluorescent spots
  • Visual field tests may show an enlarged blind spot or a decrease in visual clarity
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    Visual field tests may also show an enlarged blind spot or a decrease in visual clarity.
  • Blood tests may be ordered to check if symptoms are caused by a viral disease rather than MFC
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    doctors may order blood tests to check if the symptoms are caused by a viral disease rather than MFC.
Treatment
  • Treatments vary depending on the severity of the diagnosis
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    Treatments vary depending on the severity of the diagnosis.
  • A steroid regimen taken orally, often at low doses, is recommended as a first course of treatment
    source quote
    A steroid regimen taken orally, often at low doses, is recommended as a first course of treatment.
AI-synthesized from the Wikipedia article “Multifocal choroiditis and panuveitis”. Not medical advice. Verify source →
Multifocal choroiditis and panuveitis
SpecialtyOphthalmology

Multifocal choroiditis and panuveitis (MCP) is an inflammatory disorder of unknown etiology, affecting the choroid, retina, and vitreous of the eye that presents asymmetrically, most often in young myopic women with photopsias, enlargement of the physiologic blind spot and decreased vision.[1]

The first description of the disease was written in 1973.[2]

Symptoms include blurry vision, with or without sensitivity to light, blind spots, floaters, eye discomfort and perceived flashes of light.[2]

An ophthalmologist may use a series of imaging techniques. A test called flourescein angiography uses a special dye and camera to study blood flow in the back layers of the eye. When a person has multifocal choroiditis (MFC), lesions in the eye will appear as fluorescent spots. Visual field tests may also show an enlarged blind spot or a decrease in visual clarity. Often, doctors may order blood tests to check if the symptoms are caused by a viral disease rather than MFC.

Treatments vary depending on the severity of the diagnosis. A steroid regimen taken orally, often at low doses, is recommended as a first course of treatment. The low dose of steroids can help decrease inflammation, and as a result, lessens the visual impairment. In the event steroids are not effective, medicines may be administered via injections directly into the eye. One such treatment uses Ozurdex. A small capsule is inserted into the eye via injection, and releases medicines slowly, in the course of a few months, as the capsule dissolves.

  1. ↑ Maghsoudlou, P; Epps, SJ; Guly, CM; Dick, AD (28 May 2025). "Uveitis in Adults: A Review". JAMA. 334 (5): 419–434. doi:10.1001/jama.2025.4358. PMID 40434762.
  2. 1 2 Multifocal Choroidopathy Syndromes at eMedicine