O OftalmopediaAn open ophthalmology reference

Minimally invasive strabismus surgery

AI overview

Minimally invasive strabismus surgery (MISS) is a technique in strabismus surgery that uses smaller incisions than the classical surgical approach to correct the condition, thus minimizing tissue disruption.

Key points
  • MISS can be employed for all major types of strabismus surgery.
    source quote
    MISS is a technique that can be employed for all major types of strabismus surgery like rectus muscle recessions, resections, plications, reoperations, transpositions, oblique muscle recessions, or plications, and adjustable sutures, even in the presence of restricted motility.
  • MISS is associated with faster postoperative rehabilitation and less swelling and discomfort.
    source quote
    The smaller openings and the less traumatic procedure are in general associated with faster postoperative rehabilitation and less swelling and discomfort for the patient immediately after the procedure.
  • MISS may decrease the risk of anterior segment ischemia, particularly in patients with Graves' ophthalmopathy.
    source quote
    MISS technique may decrease the risk of anterior segment ischemia in some patients, particularly those suffering from Graves' ophthalmopathy
  • The operating microscope rather than magnifying glasses should be used by the surgeon in MISS.
    source quote
    In MISS the operating microscope rather than magnifying glasses should be used by the surgeon.
  • Long-term results of MISS are similar to conventional strabismus surgery.
    source quote
    long-term results being similar between both groups
Symptoms
  • MISS results in fewer conjunctival and eyelid swelling complications in the immediate postoperative period.
    source quote
    fewer conjunctival and eyelid swelling complications in the immediate postoperative period after MISS than after conventional strabismus surgery
  • MISS openings reduce the frequency and severity of corneal complications such as dry eye syndrome and dellen formation.
    source quote
    MISS openings markedly reduce the frequency and severity of corneal complications like, for example, dry eye syndrome and dellen formation
Treatment
  • Several small cuts are placed where the main surgical steps have to be performed, instead of one large opening of the conjunctiva.
    source quote
    Instead of one large opening of the conjunctiva as is done in conventional strabismus surgery, several small cuts are placed where the main surgical steps, usually suturing, have to be performed.
  • Openings are placed as far away from the corneal limbus as possible to minimize postoperative discomfort.
    source quote
    Openings are placed as far away from the corneal limbus as possible to minimize postoperative discomfort.
  • A tunnel is used between two keyhole openings to insert instruments for treatment of eye muscles.
    source quote
    Between two of these incisions, called keyhole openings, there is a "tunnel" used by the surgeon to insert the instrument for the treatment of the eye muscles.
  • Keyhole openings are closed with resorbable sutures at the end of the operation.
    source quote
    At the end of the operation, the keyhole openings are closed with resorbable sutures.
Red flags
  • MISS is more time-consuming than conventional surgery and more demanding on the surgeon.
    source quote
    MISS is more time-consuming than conventional surgery. Operating on the muscles through the tunnel is more demanding on the surgeon.
  • Excessive bleeding that cannot be stopped may require enlargement of the cuts to cauterize the vessel.
    source quote
    An excessive bleeding that cannot be stopped makes an enlargement of the cuts necessary to cauterize the vessel.
Prognosis

Long-term results are similar to conventional strabismus surgery, with lesser rates of complications and faster reconvalescence as main advantages.

AI-synthesized from the Wikipedia article “Minimally invasive strabismus surgery”. Not medical advice. Verify source →

Minimally invasive strabismus surgery (MISS) is a technique in strabismus surgery that uses smaller incisions than the classical surgical approach to correct the condition, thus minimizing tissue disruption. The technique was introduced by Swiss ophthalmologist Daniel Mojon around 2007,[1] after the Belgian ophthalmologist Marc Gobin described the idea in 1994 in a French-language textbook.[2]

MISS is a technique that can be employed for all major types of strabismus surgery like rectus muscle recessions, resections, plications, reoperations, transpositions, oblique muscle recessions, or plications, and adjustable sutures, even in the presence of restricted motility. The smaller openings and the less traumatic procedure are in general associated with faster postoperative rehabilitation and less swelling and discomfort for the patient immediately after the procedure. It is supposed that the technique can be performed as an outpatient intervention in many patients (mainly adults) who would otherwise be hospitalized. [3] A study published in 2017 documented fewer conjunctival and eyelid swelling complications in the immediate postoperative period after MISS than after conventional strabismus surgery with long-term results being similar between both groups.[4] Another advantage is that MISS technique may decrease the risk of anterior segment ischemia in some patients, particularly those suffering from Graves' ophthalmopathy. [5]

In MISS the operating microscope rather than magnifying glasses should be used by the surgeon. Instead of one large opening of the conjunctiva as is done in conventional strabismus surgery, several small cuts are placed where the main surgical steps, usually suturing, have to be performed. Openings are placed as far away from the corneal limbus as possible to minimize postoperative discomfort. Between two of these incisions, called keyhole openings, there is a "tunnel" used by the surgeon to insert the instrument for the treatment of the eye muscles.[6] At the end of the operation, the keyhole openings are closed with resorbable sutures. These mini-incisions are postoperatively covered by the eyelid. MISS openings markedly reduce the frequency and severity of corneal complications like, for example, dry eye syndrome and dellen formation, and will allow wearing contact lenses earlier. Long-term benefits are avoidance of an increase in redness of the visible conjunctiva and a decreased scarring of the perimuscular tissue, which will facilitate reoperations - if those should become necessary.[7]

The results after MISS regarding postoperative ocular alignment are widely described in the so far still limited literature on the technique to be about the same as in classical strabismus surgery. This was documented, for instance, in comparing 40 children; the group that had undergone the minimally invasive procedure, however, did show less swelling of the conjunctiva and the eyelids after surgery.[8] Lesser rates of complications and faster reconvalescence have been widely established as the main advantages of MISS.[9] The technique's efficacy has been shown for surgery of the rectus muscles[10][11][12] as well as for the surgery of the oblique muscles.[13] A group from India reported on the successful performance of MISS in patients with Graves' orbitopathy.[14]

MISS is more time-consuming than conventional surgery. Operating on the muscles through the tunnel is more demanding on the surgeon. The keyhole cuts may tear in older patients. If the tear involves Tenon's capsule, a visible scar may result. An excessive bleeding that cannot be stopped makes an enlargement of the cuts necessary to cauterize the vessel. Usually, a conversion to a limbal opening as in classical strabismus surgery can be avoided. There are few reports, though, on complications that are unique to MISS. [15]

  1. D. S. Mojon: Comparison of a new, minimally invasive strabismus surgery technique with the usual limbal approach for rectus muscle recession and plication. In: Br J Ophthalmol. 91(1), Jan 2007, S. 76–82.
  2. M. H. Gobin, J. J. M. Bierlaagh: Chirurgie horizontale et cycloverticale simultane´e du strabisme. Centrum voor Strabologie, Antwerp 1994.
  3. D. S. Mojon: Review: minimally invasive strabismus surgery. In: Eye. 29, 2015, S. 225–233.
  4. Gupta P, Dadeya S, Kamlesh, Bhambhawani V: Comparison of Minimally Invasive Strabismus Surgery (MISS) and Conventional Strabismus Surgery Using the Limbal ApproachJ Pediatr Ophthalmol Strabismus. 2017;54:208-215.
  5. Kushner BJ. Minimally invasive strabismus surgery. Comparison of a new, minimally invasive strabismus surgery technique with the usual limbal approach for rectus muscle recession and plication. Br J Ophthalmol 2007;91:5.
  6. Asproudis I, Kozeis N, Katsanos A, Jain S, Tranos PG, Konstas AG. A Review of Minimally Invasive Strabismus Surgery (MISS): Is This the Way Forward?Adv Ther. 2017;34:826-833.
  7. D. S. Mojon: Review: minimally invasive strabismus surgery. In: Eye. 29, 2015, S. 225–233.
  8. P. Gupta, S. Dadeya, Kamlesh, V. Bhambhawani: Comparison of Minimally Invasive Strabismus Surgery (MISS) and Conventional Strabismus Surgery Using the Limbal Approach. In: J Pediatr Ophthalmol Strabismus. 54(4), 1. Jul 2017, S. 208–215.
  9. I. Asproudis, N. Kozeis, A. Katsanos, S. Jain, P. G. Tranos, A. G. Konstas: A Review of Minimally Invasive Strabismus Surgery (MISS): Is This the Way Forward? In: Adv Ther. 34(4), Apr 2017, S. 826–833.
  10. P. Merino, I. Blanco Domínguez, P. Gómez de Liaño: Outcomes of minimally invasive strabismus surgery for horizontal deviation. In: Arch Soc Esp Oftalmol. 91(2), Feb 2016, S. 69–73.
  11. N. Pellanda, D. S. Mojon: Combined horizontal rectus muscle minimally invasive strabismus surgery for exotropia. In: Can J Ophthalmol. 45(4), Aug 2010, S. 363–367.
  12. D. S. Mojon: Minimally invasive strabismus surgery for rectus muscle posterior fixation. In: Ophthalmologica. 223(2), 2009, S. 111–115.
  13. D. S. Mojon: Minimally invasive strabismus surgery (MISS) for inferior obliquus recession. In: Graefes Arch Clin Exp Ophthalmol. 247(2), 2009, S. 261–265.
  14. M. N. Naik, A. G. Nair, A. Gupta, S. Kamal: Minimally invasive surgery for thyroid eye disease. In: Indian J Ophthalmol. 63(11), Nov 2015, S. 847–853.
  15. D. S. Mojon: Review: minimally invasive strabismus surgery. In: Eye. 29, 2015, S. 225–233.