O OftalmopediaAn open ophthalmology reference

List of systemic diseases with ocular manifestations

AI overview

An ocular manifestation of a systemic disease is an eye condition that directly or indirectly results from a disease process in another part of the body.

Key points
  • Diabetes is the leading cause of new cases of blindness in those aged 20–74.
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    Diabetes , for example, is the leading cause of new cases of blindness in those aged 20–74
  • Diabetic retinopathy and macular edema affect up to 80% of patients who have had diabetes for 15 years or more.
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    ocular manifestations such as diabetic retinopathy and macular edema affecting up to 80% of those who have had the disease for 15 years or more
  • AIDS and hypertension commonly have associated ocular symptoms.
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    Other diseases such as acquired immunodeficiency syndrome (AIDS) and hypertension are commonly found to have associated ocular symptoms.
  • Many diseases are known to cause ocular or visual changes.
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    There are many diseases known to cause ocular or visual changes.
  • 50-60% of patients with granulomatosis with polyangiitis have ophthalmologic manifestations.
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    50-60% have ophthalmologic manifestations, which can be a presenting feature in a minority of patients.
Symptoms
  • Granulomatosis with polyangiitis may cause proptosis, restrictive ophthalmopathy, and chronic orbital pain.
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    may result in proptosis , restrictive ophthalmopathy , chronic orbital pain
  • Chronic cases of granulomatosis with polyangiitis may involve orbital retraction syndrome and intractable socket pain.
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    in chronic cases, orbital retraction syndrome and intractable socket pain
  • Granulomatosis with polyangiitis may cause inflammation of the optic nerve, ophthalmoplegia, conjunctivitis, keratitis, scleritis, episcleritis, dacrocystitis, nasolacrimal duct obstruction, dacroadenitis, uveitis, and retinal vasculitis.
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    Granulomatosis with polyangiitis may also cause inflammation of the optic nerve , ophthalmoplegia , conjunctivitis , keratitis , scleritis , episcleritis , dacrocystitis , nasolacrimnal duct obstruction, dacroadenitis , uveitis , and retinal vasculitis.
Red flags
  • Ophthalmologic manifestations can be a presenting feature of granulomatosis with polyangiitis in a minority of patients.
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    which can be a presenting feature in a minority of patients.
AI-synthesized from the Wikipedia article “List of systemic diseases with ocular manifestations”. Not medical advice. Verify source →

An ocular manifestation of a systemic disease is an eye condition that directly or indirectly results from a disease process in another part of the body. There are many diseases known to cause ocular or visual changes. Diabetes, for example, is the leading cause of new cases of blindness in those aged 20–74, with ocular manifestations such as diabetic retinopathy and macular edema affecting up to 80% of those who have had the disease for 15 years or more. Other diseases such as acquired immunodeficiency syndrome (AIDS) and hypertension are commonly found to have associated ocular symptoms.[citation needed]

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  2. Ikegami, Tetsuro; Makino, Shinji (2011-05-06). "The Pathogenesis of Rift Valley Fever". Viruses. 3 (5): 493–519. doi:10.3390/v3050493. PMC 3111045. PMID 21666766.
  3. "Dengue Eye Disease". The BMJ. 2017-07-06.
  4. Mehta, Salil; Jiandani, Prakash (September 2007). "Ocular features of hantavirus infection". Indian Journal of Ophthalmology. 55 (5): 378–380. doi:10.4103/0301-4738.33827. ISSN 0301-4738. PMC 2636028. PMID 17699950.

  • Pavan-Langston, Deborah (1990). Manual of Ocular Diagnosis and Therapy. Little, Brown and Company.