Limbal nodule
AI overview
A limbal nodule is any nodular lesion at the limbus (junction of the cornea and sclera) of the eye.
Key points
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A 1989 case series examined 636 limbal nodules over 40 years at the Institute of Ophthalmology in London
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A 1989 case series of 636 limbal nodules examined over a period of 40 years at the Institute of Ophthalmology in London
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351 nodules involved melanocytes, with two-thirds being benign nevi
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351 nodules involved malanocytes with two-thirds being benign nevi
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73 lesions were squamous cell carcinomas and 137 were premalignant lesions
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Seventy three lesions were squamous cell carcinomas, and 137 premalignant lesions
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Ten percent of the lesions were dermoid nodules
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Ten percent of the lesions were dermoid nodules
Diagnosis
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Differential diagnosis includes pinguecula, early pterygium, foreign body, phlycten, episcleritis, scleritis, granuloma, limbal dermoid, malignant melanoma, and naevus
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The differential diagnosis for a limbal nodule can include: Pinguecula Early Pterygium Foreign body / foreign body granuloma Phlycten , an inflamed nodule of lymphoid tissue Episcleritis Scleritis Granuloma Limbal dermoid , a kind of choristoma (NB: in other organs dermoid can refer to a teratoma ) malignant melanoma naevus
Red flags
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Squamous cell carcinoma was found in 73 cases
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Seventy three lesions were squamous cell carcinomas
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Premalignant lesions were identified among the cases
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137 premalignant lesions
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Malignant melanoma is included in the differential diagnosis
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malignant melanoma
AI-synthesized from the Wikipedia article “Limbal nodule”. Not medical advice.
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| Limbal nodule | |
|---|---|
| Limbus | |
| Specialty | Ophthalmology |
A limbal nodule is any nodular lesion at the limbus (junction of the cornea and sclera) of the eye.
The differential diagnosis for a limbal nodule can include:
- Pinguecula
- Early Pterygium
- Foreign body / foreign body granuloma
- Phlycten, an inflamed nodule of lymphoid tissue
- Episcleritis
- Scleritis
- Granuloma
- Limbal dermoid, a kind of choristoma (NB: in other organs dermoid can refer to a teratoma)
- malignant melanoma
- naevus
A 1989 case series of 636 limbal nodules examined over a period of 40 years at the Institute of Ophthalmology in London reported that 351 nodules involved malanocytes with two-thirds being benign nevi. Seventy three lesions were squamous cell carcinomas, and 137 premalignant lesions. Ten percent of the lesions were dermoid nodules.[1]
- ↑ Garner, Alec (March 1989). "The pathology of tumours at the limbus". Eye. 3 (2): 210–217. doi:10.1038/eye.1989.30.
- Hampton Roy; Daljit Singh; Richard J. Fugo (2010). Ocular Applications of the Fugo Blade. Lippincott Williams & Wilkins. p. 42. ISBN 978-1-60547-888-3.