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Acute idiopathic blind spot enlargement syndrome

AI overview

Acute idiopathic blind spot enlargement syndrome (AIBSE) is a rare eye disease affecting the retina of the eye.

Key points
  • It is a type of retinopathy which affects females more than males.
    source quote
    It is basically a type of retinopathy which affects females more than males.
  • The exact etiology is unknown, but viral illness and vaccinations may trigger the condition.
    source quote
    Though exact etiology of AIBSE syndrome is unknown, studies shows that viral illness like influenza and vaccinations like MMR may trigger the condition.
  • Fletcher et al. first described AIBSE syndrome in 1988.
    source quote
    Fletcher et al. first described AIBSE syndrome in 1988.
  • Higher incidence is seen in Caucasian people.
    source quote
    Higher incidence is seen in Caucasian people .
Symptoms
  • Enlargement of blind spot area in the visual field is the main sign.
    source quote
    Enlargement of blind spot area in the visual field of the eye is the main sign
  • Acute onset photopsia is the main symptom.
    source quote
    acute onset photopsia is the main symptom of AIBSE syndrome
  • Other symptoms include monocular scotoma and reduced light perception.
    source quote
    Other symptoms include monocular scotoma and reduced light perception.
Diagnosis
  • Multiple diagnostic techniques may be used including ophthalmoscopy, visual field test, OCT, fluorescein angiography, multifocal electroretinography and electrophysiology.
    source quote
    Diagnostic techniques like ophthalmoscopy , visual field test , optical coherence tomography , fluorescein angiography , multifocal electroretinography and electrophysiology may be used in diagnosing AIBSE syndrome.
  • Subjective measurement of blind spot enlargement is done using visual field testing.
    source quote
    Subjective measurement of blind spot enlargement is done using visual field testing.
  • In early stages, FFA peripapillary hyperfluorescence may be observed.
    source quote
    In the early stages, using FFA peripapillary hyperfluorescence may be observed.
  • OCT is the gold standard in diagnosing AIBSES as it can observe microstructural alterations in the outer retina.
    source quote
    Since OCT can be used to observe the microstructural alterations in the outer retina, it is the gold standard in diagnosing AIBSES.
Treatment
  • There is currently no treatment, but the condition is usually self-limiting.
    source quote
    Currently there is no treatment for this condition, but, it is usually self limiting.
  • Systemic administration of corticosteroids may be advised.
    source quote
    Systemic administration of corticosteroids may be advised.
  • Even after disease resolution, the enlarged blind spot usually does not return to normal.
    source quote
    Even if the disease is resolved, the enlarged blind spot usually does not return to normal.
Prognosis

Usually self-limiting, but the enlarged blind spot typically does not return to normal even after disease resolution.

AI-synthesized from the Wikipedia article “Acute idiopathic blind spot enlargement syndrome”. Not medical advice. Verify source →
Acute idiopathic blind spot enlargement syndrome
Other namesAIBSE syndrome
SpecialtyOphthalmology
Diagnostic methodEye examination, Visual field test
TreatmentNil, Usually self limiting

Acute idiopathic blind spot enlargement syndrome (AIBSE) is a rare eye disease affecting the retina of the eye. It is basically a type of retinopathy which affects females more than males. Currently there is no treatment for this condition, but, it is usually self limiting.

Enlargement of blind spot area in the visual field of the eye is the main sign and acute onset photopsia is the main symptom of AIBSE syndrome.[1] Other symptoms include monocular scotoma and reduced light perception.[2]

Though exact etiology of AIBSE syndrome is unknown, studies shows that viral illness like influenza and vaccinations like MMR may trigger the condition.[3]

Diagnostic techniques like ophthalmoscopy, visual field test, optical coherence tomography, fluorescein angiography, multifocal electroretinography and electrophysiology may be used in diagnosing AIBSE syndrome.[1] Subjective measurement of blind spot enlargement is done using visual field testing.[4] In the early stages, using FFA peripapillary hyperfluorescence may be observed.[4] Since OCT can be used to observe the microstructural alterations in the outer retina, it is the gold standard in diagnosing AIBSES.[1]

Currently there is no treatment for this condition, but, it is usually self limiting.[3] Systemic administration of corticosteroids may be advised.[1] Even if the disease is resolved, the enlarged blind spot usually does not return to normal.[5]

AIBSE syndrome affects females more than males.[3] Higher incidence is seen in Caucasian people.[3]

Fletcher et al. first described AIBSE syndrome in 1988.[1]

  1. 1 2 3 4 5 Zimmermann, Julian A.; Eter, Nicole; Biermann, Julia (7 September 2022). "Acute Idiopathic Blind Spot Enlargement Syndrome—New Perspectives in the OCT Era". Journal of Clinical Medicine. 11 (18): 5278. doi:10.3390/jcm11185278. ISSN 2077-0383. PMC 9501978. PMID 36142923.
  2. ↑ Wong, Melody; Campos-Baniak, Maria Gabriela; Colleaux, Kevin (August 2019). "Acute idiopathic blind spot enlargement syndrome following measles, mumps and rubella vaccination". Canadian Journal of Ophthalmology. 54 (4): e199–e203. doi:10.1016/j.jcjo.2018.09.005. PMID 31358170.
  3. 1 2 3 4 "Acute Idiopathic Blind Spot Enlargement (AIBSE) Syndrome - EyeWiki". eyewiki.aao.org.
  4. 1 2 Ishihara, Rhys; Khan, Youan; Halim, Muhammad Sohail; Akhavanrezayat, Amir; Onghanseng, Neil; Levin, Marc Harris; Nguyen, Quan Dong (March 2023). "Acute idiopathic blind spot enlargement syndrome (AIBSES) with retinal vasculitis". American Journal of Ophthalmology Case Reports. 29 101760. doi:10.1016/j.ajoc.2022.101760. ISSN 2451-9936. PMC 9763352. PMID 36561880.
  5. ↑ "The Case of the Enormous Blind Spot". Retina Today.