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Acorea

AI overview

Acorea or acoria is an eye disease defined as the absence of the pupil, unilaterally or bilaterally.

Key points
  • Acorea can be a birth defect, which is very rare, as in iridocorneal dysgenesis or persistent pupillary membrane.
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    It can be birth defect , which is very rare, as is the case with iridocorneal dysgenesis or due to a persistent pupillary membrane.
  • Acorea can also be acquired due to pathology or injury affecting the iris, such as inflammation or ocular trauma.
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    and also acquired origin, product of a pathology or injury that is affecting the iris, such as inflammation or ocular trauma
  • Acorea must be differentiated from pupillary pseudoacorea, in which the pupil is hidden but becomes evident after pharmacological mydriasis.
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    It must be differentiated from pupillary pseudoacorea or pseudoacoria or "hidden pupil", which is a rare condition in which the pupil is not visible at rest and only becomes evident after pharmacological mydriasis.
Symptoms
  • The pupil is completely absent in true acorea.
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    This distinguishes it from true acorea, in which the pupil is completely absent.
Diagnosis
  • Differentiation from pseudoacorea is made using pharmacological mydriasis, which reveals a hidden pupil in pseudoacorea but not in true acorea.
    source quote
    which is a rare condition in which the pupil is not visible at rest and only becomes evident after pharmacological mydriasis
Treatment
  • Surgical interventions for acorea are sometimes undertaken in the context of Axenfeld–Rieger syndrome.
    source quote
    Surgical interventions for acorea are sometimes undertaken in the context of Axenfeld–Rieger syndrome
AI-synthesized from the Wikipedia article “Acorea”. Not medical advice. Verify source →

Acorea or acoria is an eye disease defined as the absence of the pupil, unilaterally or bilaterally. It can be birth defect, which is very rare, as is the case with iridocorneal dysgenesis or due to a persistent pupillary membrane.[1][2] and also acquired origin, product of a pathology or injury that is affecting the iris, such as inflammation or ocular trauma.[3] It must be differentiated from pupillary pseudoacorea or pseudoacoria or "hidden pupil", which is a rare condition in which the pupil is not visible at rest and only becomes evident after pharmacological mydriasis. This distinguishes it from true acorea, in which the pupil is completely absent.[4][5]

Surgical interventions for acorea are sometimes undertaken in the context of Axenfeld–Rieger syndrome.[6][5]

  1. Ramasubramanian, Srikanth; Majumder, ParthopratimDutta (October 12, 2018). "Acorea: A rare congenital anomaly". Indian Journal of Ophthalmology. 66 (3): 450. doi:10.4103/ijo.IJO_900_17. PMC 5859608.
  2. Kondo, Hiroyuki; Tahira, Tomoko; Yamamoto, Ken; Tawara, Akihiko (September 1, 2013). "Familial acorea, microphthalmia and cataract syndrome". British Journal of Ophthalmology. 97 (9): 1155–1160. doi:10.1136/bjophthalmol-2013-303165. PMID 23832966 via bjo.bmj.com.
  3. Morais, Luciana Negrão Almeida; David, Joacy Pedro Franco; Peres Lima, João Victor; Demachki, Samia; Diniz, Daniel Guerreiro; Almeida, Edmundo Frota de (November 12, 2022). "Acquired acoria and iris pearls in leprosy: Case report". European Journal of Ophthalmology. 32 (6): NP36–NP40. doi:10.1177/11206721211024057. PMID 34142579.
  4. Alza, Andrés Germán (October 12, 2023). "Case Report: Congenital Pseudoacorea in an Ocular Axenfeld-Rieger Syndrome: What is it?". Journal of Clinical Cases & Reports. 6 (4): 173–186. doi:10.46619/joccr.2023.6-1145. PMC 10473882. PMID 37663013.
  5. 1 2 Andres German Alza (2025) Retroiridian Pupilloplasty for Phakic Traumatic Pseudoacorea: A Novel Minimally Invasive Surgical Technique. J Clin Cases Rep 8(3): 103-110.
  6. Alza, Andrés Germán; Galletto, Eduardo (November 8, 2022). "Pupiloplastia retroiridiana". Oftalmología Clínica y Experimental. 15 (1). doi:10.70313/2718.7446.v15.n1.182 via revistaoce.com.