Boston's sign
AI overview
Boston's sign is the spasmodic lowering of the upper eyelid on downward rotation of the eye, indicating exophthalmic goiter.
Key points
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Boston's sign is similar to von Graefe's sign.
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Similar to von Graefe's sign
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In Graves-Basedow disease, the immune system attacks the thyroid gland and the soft tissues surrounding the eyes.
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the immune system attacks the thyroid gland and the soft tissues surrounding the eyes
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The eyes are often pushed forward in the eye sockets, a condition known as exophthalmos.
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the eyes are often pushed forward in the eye sockets, a condition known as exophthalmos
Symptoms
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Spasmodic lowering of the upper eyelid occurs on downward rotation of the eye.
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the spasmodic lowering of the upper eyelid on downward rotation of the eye
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Eyes may be pushed forward in the eye sockets (exophthalmos).
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the eyes are often pushed forward in the eye sockets, a condition known as exophthalmos
Diagnosis
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Boston's sign indicates exophthalmic goiter.
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indicating exophthalmic goiter
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It is observed in people with Graves-Basedow disease.
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it is observed in people with Graves-Basedow disease
AI-synthesized from the Wikipedia article “Boston's sign”. Not medical advice.
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| Boston's sign | |
|---|---|
| Differential diagnosis | exophthalmic goiter |
Boston's sign is the spasmodic lowering of the upper eyelid on downward rotation of the eye, indicating exophthalmic goiter.[1]
Similar to von Graefe's sign, it is observed in people with Graves-Basedow disease, a type of hyperthyroidism. In this disease, the immune system attacks the thyroid gland and the soft tissues surrounding the eyes. As a result, the eyes are often pushed forward in the eye sockets, a condition known as exophthalmos.[citation needed]
- ↑ Cline D; Hofstetter HW; Griffin JR. Dictionary of Visual Science. 4th ed. Butterworth-Heinemann, Boston 1997. ISBN 0-7506-9895-0